Edilia Tapia Selected Research

Oxonic Acid

1/2018	Probiotic supplements prevented oxonic acid-induced hyperuricemia and renal damage.
1/2015	Renal oxidative stress induced by long-term hyperuricemia alters mitochondrial function and maintains systemic hypertension.
10/2008	Role of oxidative stress in the renal abnormalities induced by experimental hyperuricemia.
4/2008	Treatment with the xanthine oxidase inhibitor febuxostat lowers uric acid and alleviates systemic and glomerular hypertension in experimental hyperuricaemia.
1/2008	Effect of febuxostat on the progression of renal disease in 5/6 nephrectomy rats with and without hyperuricemia.
1/2005	Hemodynamics of hyperuricemia.
1/2005	Mild hyperuricemia induces vasoconstriction and maintains glomerular hypertension in normal and remnant kidney rats.
11/2002	Mild hyperuricemia induces glomerular hypertension in normal rats.

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Edilia Tapia Research Topics

Disease

27	Hypertension (High Blood Pressure) 02/2021 - 10/2001
16	Proteinuria 10/2018 - 10/2001
13	Inflammation (Inflammations) 01/2022 - 03/2003
13	Hyperuricemia 02/2021 - 11/2002
12	Chronic Renal Insufficiency 05/2022 - 08/2013
10	Mitochondrial Diseases (Mitochondrial Disease) 05/2019 - 08/2011
9	Ischemia 01/2022 - 10/2003
7	Fibrosis (Cirrhosis) 11/2020 - 10/2001
6	Metabolic Syndrome (Dysmetabolic Syndrome X) 05/2022 - 01/2007
6	Dehydration (Water Stress) 01/2020 - 01/2016
5	Diabetic Nephropathies (Diabetic Nephropathy) 11/2020 - 09/2013
5	Acute Kidney Injury (Acute Renal Failure) 11/2020 - 01/2012
4	Neoplasms (Cancer) 09/2017 - 05/2012
4	Renal Hypertension 01/2015 - 11/2007
3	Hyperglycemia 02/2021 - 10/2018
3	Body Weight (Weight, Body) 02/2021 - 08/2011
3	Hypoxia (Hypoxemia) 11/2020 - 02/2017
3	Glycosuria 10/2018 - 10/2014
2	Obesity 05/2022 - 02/2021
2	Hypertriglyceridemia 02/2021 - 01/2007
2	Kidney Diseases (Kidney Disease) 02/2021 - 01/2016
2	Necrosis 01/2020 - 01/2013
2	Autosomal Dominant Optic Atrophy (Dominant Optic Atrophy) 09/2017 - 03/2017
2	Chronic Kidney Failure (Chronic Renal Failure) 09/2013 - 02/2013
2	Atrophy 02/2013 - 06/2002
2	Reperfusion Injury 01/2012 - 12/2011
2	Sclerosis 01/2012 - 06/2002
1	Cardiovascular Diseases (Cardiovascular Disease) 05/2022
1	Ureteral Obstruction 07/2021
1	Fanconi Syndrome (Syndrome, Fanconi) 01/2020
1	Polyuria 10/2018
1	Familial Hypophosphatemia (Phosphate Diabetes) 05/2018

Drug/Important Bio-Agent (IBA)

17	AntioxidantsIBA 01/2022 - 11/2005
15	CurcuminIBA 11/2020 - 10/2011
10	FructoseIBA 05/2022 - 01/2007
10	CreatinineIBA 01/2020 - 11/2006
9	EnzymesIBA 07/2021 - 11/2005
8	Proteins (Proteins, Gene)FDA Link 11/2020 - 10/2003
8	Oxonic AcidIBA 01/2018 - 11/2002
5	fructokinaseIBA 02/2021 - 03/2013
5	Cisplatin (Platino)FDA LinkGeneric 05/2019 - 08/2011
5	Hexosaminidases (Hexosaminidase)IBA 10/2018 - 01/2012
5	Glutathione PeroxidaseIBA 05/2018 - 08/2011
5	Uric Acid (Urate)IBA 01/2018 - 01/2005
5	Urate Oxidase (Uricase)IBA 01/2018 - 01/2005
5	Urea (Carbamide)FDA LinkGeneric 09/2017 - 11/2007
5	NitrogenIBA 09/2017 - 11/2007
5	Mycophenolic Acid (Cellcept)FDA LinkGeneric 07/2016 - 11/2001
5	Angiotensin IIIBA 01/2016 - 11/2001
5	Oxidants (Oxidizing Agents)IBA 07/2013 - 08/2011
4	Vasopressins (Vasopressin)IBA 05/2022 - 01/2016
4	allicinIBA 11/2020 - 01/2016
4	Potassium Dichromate FDA Link 11/2020 - 11/2014
4	sulforaphaneIBA 01/2020 - 08/2011
4	Allopurinol (Remid)FDA LinkGeneric 01/2018 - 11/2002
4	SaltsIBA 04/2013 - 11/2001
3	Insulin (Novolin)FDA Link 11/2020 - 04/2008
3	nephrinIBA 11/2020 - 01/2016
3	maleic acid (maleate)IBA 01/2020 - 11/2016
3	Drinking WaterIBA 01/2015 - 01/2007
3	Adenosine Triphosphate (ATP)IBA 01/2015 - 10/2011
3	chromium hexavalent ionIBA 11/2014 - 10/2011
3	SodiumIBA 10/2014 - 01/2005
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 10/2008 - 11/2006
3	Febuxostat FDA Link 04/2008 - 01/2008
3	Xanthine OxidaseIBA 04/2008 - 01/2008
2	polyolIBA 05/2022 - 01/2020
2	SugarsIBA 02/2021 - 01/2016
2	Mitogen-Activated Protein Kinase 3IBA 01/2020 - 01/2019
2	Folic Acid (Vitamin M)FDA LinkGeneric 01/2020 - 01/2019
2	Vasopressin Receptors (Arginine Vasopressin Receptor)IBA 11/2019 - 01/2017
2	Losartan (Cozaar)FDA LinkGeneric 09/2017 - 06/2002
2	Aldehyde Reductase (Aldose Reductase)IBA 01/2017 - 01/2016
2	Glucose (Dextrose)FDA LinkGeneric 01/2016 - 03/2013
2	tempolIBA 01/2015 - 10/2008
2	Therapeutic UsesIBA 09/2013 - 05/2012
2	Triglycerides (Triacylglycerol)IBA 03/2013 - 04/2008
2	salicylhydroxamic acid (SHAM)IBA 06/2011 - 12/2006
2	3-nitrotyrosineIBA 11/2008 - 11/2007
2	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 11/2008 - 11/2007
1	KetonesIBA 01/2022
1	CarbohydratesIBA 01/2022
1	ketohexokinaseIBA 02/2021
1	osthol (osthole)IBA 02/2021
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 11/2020
1	Erythropoietin FDA Link 11/2020
1	Connective Tissue Growth FactorIBA 11/2020
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2020
1	Hydrocortisone (Cortisol)FDA LinkGeneric 11/2019
1	Sirolimus (Rapamycin)FDA Link 01/2019
1	Interleukin-6 (Interleukin 6)IBA 10/2018
1	InterleukinsIBA 10/2018
1	InflammasomesIBA 01/2018
1	Sodium Bicarbonate (Baking Soda)FDA LinkGeneric 01/2018

Therapy/Procedure

9	Nephrectomy 04/2021 - 10/2001
3	Therapeutics 01/2016 - 12/2013
3	Punctures 01/2005 - 06/2002
2	Fluid Therapy (Oral Rehydration Therapy) 11/2019 - 01/2016
1	Ketogenic Diet 01/2022
1	Injections 01/2018